Home Wellness Advanced Bionutrionals CircO2 Reviews: Ingredients, Side Effects & Customer Reviews

Advanced Bionutrionals CircO2 Reviews: Ingredients, Side Effects & Customer Reviews

Written by The Well Team

“Another day! I hope I will get through this one well!”

This had become my waking up thoughts over the past two years.

Creaking joints and low energy were part of my day.

I had crossed the milestone 60th birthday but things seemed pretty low, while my BP was soaring at times.

I definitely missed the spring in my step and zing in my life.

This was not the way I had imagined myself after retirement.

I had to do something about this.

With my partner by my side, I embarked on a search for a natural supplement to get back as close to the life I had earlier.

There were a few notable examples of elderly people with vigor, vitality, and energy around me.

What was it they were doing that I was missing out on?

Apparently, they were using supplements to boost their nitric oxide levels, which was an ingredient that could do wonders for an aging body.

I zeroed in on CircO2 after extensive research on what it was all about.

To say it has benefited me would be to state the obvious.

There has been such an amazing turnaround, not only in the physicality but also in the way my mood and focus improved.

Read on to know all about this product:

CircO2 Review – Does It Really Work?


What is CircO2?

CircO2 is a nutritional supplement formulated to maintain nitric oxide levels in the body at healthy levels.

It is made of essential minerals and vitamins sourced completely naturally.

This ensures there are no side effects for the user while helping them function better in their daily lives with more energy.

Users across the board report improved vitality and a more positive outlook towards life.

Who created it?

CircO2 has been created and manufactured by a wellness supplement company known as Advanced Bionutritionals under the guidance of Dr. Janet Zand.

This company is known for its wide range of products which are made from natural ingredients and aim to fill in the nutrition gap that normal lifestyles create.

In fact, they have coined a patented term, Nutraceuticals, to describe their products.

CircO2 and other products under this umbrella are designed by physicians with their in-depth understanding of the requirements of the human body.

CircO2 is a stellar product from their stable that is backed by science combined with good intent.

Why was CircO2 Created?

CircO2 has been formulated by a set of physicians with the intent of providing adequate nitric oxide supply to our bodies.

Nitric oxide is vital in keeping the immune system in top working order, thus facilitating youthfulness and negating the effects of aging.

As we all know, aging is an inevitable aspect of life, as are the signs of growing old.

Studies have established the important role that nitric oxide plays in boosting and maintaining the immune system.

The need for a product that encouraged nitric oxide production in the body while being free of side effects was strongly felt.

It was to address this issue that Advanced Bionutritionals came up with this product.

What happens inside the body when we age?

Getting old and possibly infirm and having to depend upon others, are things that scare the best of us.

Unfortunately, these are inevitable as we get on in years.

What we gain in life experiences can get a bit dulled by a lack of energy as part of aging.

There is less energy, more aches, less zest for living, and definitely an inability to perform in bed.

These and more symptoms can be attributed to lower levels of certain hormones as well as inadequate levels of essential minerals.

Additionally, it has been found that low nitric oxide levels affect energy levels, blood circulation, and endurance.

Studies show a steady depletion in nitric oxide levels over time.

Nutritional deficiencies are a reason for this since the food we take is not enough to provide the amount of nitric oxide needed for a healthy functioning body.

With a lesser flow of blood, different parts of the body can feel starved of nutrition, leading to below-par functioning.

Additionally, there is more joint pain and difficulty with mobility as part of the aging process.

This leads to reluctance in getting up and going every morning for a thing as simple as a walk.

Nitric Oxide – a magic nutrient?

Nitric Oxide

Scientists believe that nitric oxide has benefits with far-reaching positive consequences.

This nutrient is mostly found in the form of L-citrulline and L-arginine from foods we eat.

That amount might not be enough though, for a healthy dose and to keep aging-related tiredness at bay.

This is where supplements containing nitric oxide come into play.

Nitric oxide is quite a magical nutrient that is beneficial to the body.

Listed below are some of its effects:

  • It increases blood flow by dilating blood vessels. This helps in more blood supply to different parts of the body.
  • This helps to nourish muscles and provide more energy. It also helps with better erections in men.
  • This property can help to increase blood flow to the heart thus improving heart health.
  • It can help people to be more energetic and work out with more vigor.
  • Nitric oxide may also help in weight loss.
  • It facilitates faster healing after any injury.
  • It can also help improve retention and memory.
  • Nitric oxide can also help fight common colds better.

As we get on in age, there is decreased production of nitric oxide in the body.

There is an interface called endothelium that helps in the transfer of nutrients from the blood to the tissues.

This is also the site where nitric oxide is produced.

As the body ages, the endothelium also gets older and less efficient in functioning.

This immediately affects the production of nitric oxide, causing suboptimal blood circulation in the body.

Additional research backed by scientists at MIT has brought forth another surprising facet of the human body.

Overuse of mouthwashes has been found to kill some good bacteria in the mouth, through which all food and nutrients enter the body.

Depletion of good bacteria can further cause less production of nitric oxide in the body, again leading to feelings associated with getting older – tiredness, aches, inability to focus, and memory issues among others.

Harnessing this magic molecule nitric oxide is the working principle on which CircO2 is based.

Under the guidance of Dr. Janet Zand, Advanced Bionutrionals has created this supplement to help people combat the signs of aging and live life to the fullest.

How does CircO2 work in fighting aging symptomatology?

There is an accepted association between the onset of health issues and the advancement of age.

This is the way of explaining away increased feelings of fatigue, lack of energy and endurance, and generally feeling lackadaisical.

“Ah it is nothing, I am just getting on in years” had been the usual way of justifying these.

That was sort of okay when one experienced these beyond the 60+ age bracket.

Modern lifestyles, stressors, exposure to pollution, and general lack of nutrition have unfortunately brought that forward by some decades.

It is totally normal to hear 30-somethings complain of lack of energy, motivation, and simply feeling ‘washed out’ at the end of a workday.

This is something that CircO2 is designed to address.

  • Nitric oxide present in the formula helps to dilate blood vessels, thus enabling an increased flow of oxygen. More blood flow means better nourishment to muscles including additional nutrients. This helps to make the user more energetic to carry on with their daily routine.
  • CircO2 contains magnesium that is a heart-healthy ingredient. Along with nitric oxide, this helps in boosting heart health by reducing blood pressure and making arteries less stiff. A robust heart also helps users remain more physically active.

The scientific approach along with harnessing the goodness of nature has resulted in this wonderful product.

CircO2 Ingredients

I am listing below the star ingredients of CircO2:

1) Magnesium


This is such a vital nutrient in our body that it is surprising how lacking we are in having adequate amounts.

It has been found that the majority of us are hugely deficient in magnesium.

CircO2 is formulated to compensate for this.

Magnesium enables good heart function and keeps the brain and joints in good working condition.

2) Sodium Nitrite


Another ingredient in this proprietary formula that boosts nitric oxide levels in the body.

It is present in a specific proportion in order to provide just the right amount of nitric oxide to the body.

2) L-Arginine


A known source of natural nitric oxide, L-arginine is included in the CircO2 formula.

It helps to provide part of the nitric oxide component that the supplement promises to deliver.

3) Vitamin C

Vitamin C

Everyone knows about the antioxidative properties of vitamin C.

It helps counter free radical buildup in the body.

It also promotes a healthier environment for the production of nitric oxide in the body.

This it does by mimicking the action of a particular enzyme that produces nitric oxide in the body.

4) Vitamin B12

Vitamin b12

With a dose of 1000 mcg vitamin B12 in each pill, CircO2 packs in a punch.

With advancing years, these levels dip naturally in the body.

An adequate amount of vitamin B12 is needed to provide power to the body as well as to promote the synthesis of nitric oxide in the body.

Body parts like muscles and nerves need vitamin B12 supplementation in order to work to their full potential.

5) L-Citrulline

Citrulline-DL Malate

This ingredient helps to control blood pressure, thus enabling a better functioning body.

It also improves memory and helps better concentration.

L-citrulline has also been shown to boost sexual vitality and endurance.

6) Beet Root Powder Extract

Beet root Powder Extract

One of the wonders of nature, this natural ingredient is a powerhouse of nitric oxide.

With boosted levels of nitric oxide, there is a surge of energy.

Users experience better endurance and the ability to put in more physical effort.

Beetroot powder also promotes sharp memory and the ability to focus.

7) Hawthorn Berry Extract

Hawthorn Berry

This ingredient helps boost blood flow across veins.

With blood circulation going strong, every muscle and tissue in the body is better oxygenated.

This naturally promotes better functioning of the overall system.

Additionally, hawthorn berry extract helps to boost the effects of beetroot powder as well as L-citrulline.

In addition to these, there are other ingredients like modified cellulose, magnesium vegetable stearate, mannitol, silica, stevia, natural flavors, and colors.

The fact that CircO2 uses all-natural products along with balancing these essential vitamins and nutrients to deliver the maximum punch helped me to decide in its favor.

I already knew about Advanced Bionutritionals and the trusted range of products they were known for.

Who should not use CircO2?

Advanced Bionutritionals is known for its safe and healthy dietary supplements.

All the ingredients that go into CircO2 are extracted from natural sources and there should be no problems as such.

However, certain people should not use this, or do so under medical guidance:

  • CircO2 is not for those under 30.
  • If anyone has allergies to any of the ingredients, they should stay away from CircO2.
  • Those having preexisting conditions must consult their physician before taking CircO2.
  • Those with kidney problems must not take CircO2.

The Cons

  • This product is only available for purchase online. While most customers feel okay with this, there are still some who would prefer to visually and physically check out a new product before making a decision.
  • Much of the positives are anecdotal and there is a lack of comprehensive scientific study or related data to support these.

CircO2 Reviews from Customers

James H., Erie, PA

“Since taking Circo02 I have improved in many areas of my life pertaining to my weight lifting at the gym and my wife’s happiness. It’s an overall feeling I know the circo2 is operating…… I also feel like a new man. Thank You:”)

Barney K., Canada

“This is an excellent supplement that really works fast and gives me immediate energy that lasts for hours. I take one in the morning and slowly let it dissolve. Try it I recommend it!”

John H., McKinney, TX

“This supplement helps my blood pressure and blood flow. I am now at a level with the optimum amount of nitric oxide in my system. I will continue to use it as needed. Thanks.”

These are just some of the many happy users who have left positive reviews on the CircO2 website as well as other places.

When I was going through the research phase on this product, it was the obvious positivity among customers that encouraged me to go ahead and try this product.

The energy and positivity I feel is something that I never imagined possible at the age of 63, especially given how low I had been feeling before I began on this.

I would definitely recommend CircO2 very strongly.

It has just the right balance of nitric oxide and other essential nutrients to create and sustain a bounce back.

What are the pros of CircO2?

  1. CircO2 has been formulated under the guidance and approval of Dr. Janet Zand, OMD, L.Ac.
  2. It is made from natural healthy ingredients.
  3. It is very easy to consume since it comes in the form of pills.
  4. It is suitable and beneficial for both genders.
  5. Using CircO2 has been shown to increase energy.
  6. Users remain more active with less fatigue.
  7. It helps bridge the nutrition gap.
  8. CircO2 improves blood circulation throughout the body.
  9. Using this product leads to better insulin and human growth hormone production.
  10. There is better memory and improved retention after being on CircO2.
  11. Increased blood flow facilitates better healing.
  12. CircO2 also helps address inflammation in the body.
  13. It has been shown to reduce blood pressure.
  14. This supplement can also help address erectile dysfunction issues.

There are obviously a large number of positives of this nitric oxide-based supplement.

However, the fact that it has an optimum quantity of this along with other essential nutrients to help fulfill the deficiencies that creep into our bodies is what appealed to me most.

CircO2 reviews

Insider Information

While nitric oxide levels get boosted with CircO2, some people do wonder if too much of anything would be good.

This is justified and thankfully, there is nothing to worry about when one is taking a product from Advanced Bionutritionals.

Qualified physicians have formulated this product, and there is constant monitoring of the quality and effectiveness of CircO2 across a wide range of users.

Buying Advice

Even as we speak there is a free offer of a guide to right eating in order to get the nutrients that our body might miss in the daily course of life.

This is the time to grab this and other attractive offers.

These are only available on the direct website.

For every purchase of CircO2, whether one is buying a standalone bottle or making bulk buys, I would advise buying only from the website.

This product is not available in physical stores and can only be bought online.

It is important to stick to the website to get genuine products as well as the best prices and offers.

The website runs special discounts and offers frequently and one may avail of these easily without the fear of getting duped.


I am a whole new person after being on CircO2 for the past 3 months.

Not only my partner but my friends and family are quite taken by the new energetic and younger me that they see now.

From my personal experience, it has been truly a revelation and I would certainly recommend CircO2 to those who find themselves in my previous situation.

Give this wonderful and completely safe supplement a try and you will certainly be thanking me in a few months’ time, I promise!

Frequently Asked Questions (FAQs)

Is this supplement legit?

Yes, this is a completely safe, natural, and legitimate product that is manufactured by Advanced Bionutritionals.

The company is a leading name in the health supplement industry. It follows stringent safety measures under GMP conditions.

How can one take it?

This supplement comes in the form of pills. One needs to take 1-2 pills in the mornings, before beginning their workout.

Does it ship worldwide?

Yes, this product does ship worldwide although timings will obviously differ depending upon location.

Within the US, shipments take anywhere from 2-10 days while outside of the US, they may take as long as 21 days in some cases.

The customer needs to keep these factors in mind while placing their order so that continuity is ensured.

What is the Auto-Ship Plan?

Advanced Bionutritionals has an Auto-Ship plan detailed upon its website that applies to its product range. There are multiple safe payment options available for customers.

A run-through of the website will help users get a clear idea.

Why are nitric oxide strips provided?

For anyone having doubts about the product, the packaging includes nitric oxide strips to check for adequate levels.

Seeing on your own is the best way.

What is the refund/return policy?

There is a 90-day refund policy for CircO2 for those who are not happy with the product.

Even if one returns empty boxes, the company promises a fast refund sans shipping charges.

CircO2 reviews

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