A present study shows that nitric oxide can cause arterial stiffness, which is associated with an increased risk of heart disease and other potential side effects on the cardiovascular system.
It is the effects of nitric oxide supplements or inhaled nitric oxide on the blood vessels that affect blood flow, causing a change in blood pressure.
As such, one can develop high blood pressure, or it may lower blood pressure, depending on the amount in the blood and how much damage has been sustained.
Inflammation and cardiovascular disease are related, and the presence of chronic inflammation increases the risk of atherosclerosis.
Systemic inflammatory conditions can also affect the heart muscle and lead to an increased risk of cardiovascular events.
The relationship between nitric oxide and inflammation is not fully understood, but it is thought to be complex; as such, more research is needed.
Nitric oxide has a variety of effects on inflammation and pain, affecting the human body. However, it is unclear how much of an impact NO has on arterial stiffness.
Symptoms to look for
If your arteries have been damaged, you may experience low or high blood pressure.
6) Nausea, Vomiting, and Diarrhea
Although nitric oxide may be beneficial in small doses to people with underlying health conditions, those small doses could still be a problem.
Quite often, nitric oxide causes nausea and vomiting.
Nitric oxide may cause diarrhea and vomiting and is also dangerous for children because it can damage the brain.
If you experience these side effects from using nitric oxide supplements or L-arginine supplements, it’s best to seek out natural ways of increasing your nitric oxide intake.
what to eat
You should consume nitrate-rich foods, such as broccoli, cauliflower, leafy greens, and peas.
7) Vasodilation and Bleeding
The cell wall of blood vessels, called the endothelium, produces nitric oxide.
The endothelium regulates blood flow and produces nitric oxide in response to changes in the surrounding environment.
In healthy individuals, excess nitric oxide promotes blood vessel dilation and expands blood vessels, thereby decreasing plaque growth and blood clotting.
It is this dilation that also helps to treat erectile dysfunction.
However, when an individual experiences emotional distress, this membrane produces less nitric oxide and accelerates the onset of atherosclerosis (plaque build-up inside your arteries).
Despite the importance of nitric oxide, the role of NO in blood flow is unclear. Nonetheless, it seems elevated levels of nitric oxide is potentially harmful to those on heart medications.
Research suggests that it contributes to the healing of ulcers, slows nerve damage, and maintains circulation to organs below normal levels.
But, the question remains: How does nitric oxide contribute to normal hemodynamics? The answer is complex, but no one knows exactly.
It has a surprisingly large role in human physiology and may even exacerbate kidney disease and decrease heart health.
If you already have low blood pressure, then you should avoid using nitric oxide.
Symptoms to look for
But the experts do know that nitric oxide leads to blood vessel dilation, and as such, you may experience increased blood pressure, headaches, and unusual bleeding.
8) Muscle Ischemia
Nitric oxide is a component of cellular signaling that plays an important role in skeletal muscle contraction.
Several types of NO are found in the muscle cells and are anchored to a protein called dystrophin.
These proteins form a protein complex called dystrophin, which is mutated in Duchenne muscular dystrophy and other disorders.
Nitric oxide remains localized to one area of the muscle, where it may lead to a lack of oxygen, especially in the working muscles.
Symptoms to look for
If nitric oxide is causing muscle ischemia, you may experience burning or tingling aches, muscle tension, or stiffness that feel like knots in your legs, thighs, shoulders, and back.
Nitric oxide production happens naturally throughout the human body; however, it needs to be supplemented, and for that reason, we use supplements and amino acids.
Nitric oxide also has a range of health benefits and therapeutic applications, including treating erectile dysfunction, improving exercise performance, enhancing heart health, and regulating blood pressure.
Unfortunately, whether ingested or inhaled nitric oxide, in excess, nitric oxide can cause severe adverse effects.
Since nitric oxide is present in almost all body cells, it can cause side effects on any system.
Speak to your healthcare provider before using nitric oxide, especially if you have less than normal blood pressure.
When you consume nitrate, your body converts it to nitric oxide, and that causes your blood vessels to relax and dilate, lowering blood pressure.
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