Home Bodybuilding Cardarine SARMs (GW501516) Review: Dosage, Side Effects, Safe Alternatives

Cardarine SARMs (GW501516) Review: Dosage, Side Effects, Safe Alternatives

Written by Decyry Jhoy Serrano, RPh

Performance-seeking athletes tend to look for a drug that can improve not just their muscle health but also their bone health.

Fortunately, selective androgen receptor modulators (SARMs) are effective substances.

One of these SARMs is Cardarine, and according to a study in Switzerland, this drug can promote weight loss and increase muscle growth.

In this article, you will learn more about Cardaine and its legal alternative.

Cardarine Safe & Legal Alternative

The best safe and legal alternative to Cardarine (GW501516) is C-DINE 501516.

Here’s why:

  • C-DINE is Safe & Natural CARDARINE GW501516 Alternative
  • Extreme excess fat torcher
  • Enhances muscle definition
  • Shed pounds faster

So make sure to check it out. It might just be the best money you’ll spend in 2022.

Cardarine SARMs Review – All You Should Know + Safe Alternatives

Cardarine GW-501516: What is it For?

Also known as Endurobol, Cardarine GW-501516 is a PPARδ receptor agonist that is mainly used for performance enhancement.

Generally, it acts as a selective androgen receptor modulator and works by increasing muscle mass and burning body fat.

This drug was invented by Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, and as of today, Cardarine is still an investigational drug.

Thus, it is not safe for human use as there are no human studies yet.

Cardarine GW-501516 Indications

Aside from increasing lean muscle mass, Cardarine GW-501516 is also used for the following indications:

  • Wound healing
  • Inflammatory diseases
  • Fatigue
  • Obesity
  • Cardiovascular diseases
  • Liver injury prevention

Looking at these, it is interesting to say that Cardarine GW-501516 is far different from other selective androgen receptor modulators.

Most of these SARMs may cause a heart attack or liver injury, but this one does the opposite.

Can Everyone Use this Selective Androgen Receptor Modulator?

Although Cardarine GW-501516 can provide many health benefits not just to muscle and heart health, not everyone can experience these benefits.

In this section, we will discuss the contraindications of Cardarine GW-501516.

1) Pregnant and lactating women

Cardarine GW-501516 is under pregnancy category X.

This means that this drug comes with teratogenic effects that may harm the fetus.

In animal studies, it was found that taking Cardarine GW-501516 during pregnancy, especially at high doses, can impose health risks on fetal development.

2) Patients below 18 years old

Cardarine GW-501516 is still an investigational drug and has not been approved by the FDA for human consumption.

This means that purchasing this substance may only be for research purposes.

Along with this, Cardarine GW-501516 should not be used by patients below 18 years old.

For patients below 18 who wish to take this drug for medical use, it is highly advised to seek medical consultation to avoid dangerous events.

3) Cancer patients

Cardarine GW-501516 is said to be an effective drug for inhibiting cancer cell growth.

However, there are also speculations that this drug can increase the spread of tumors in the brain cells.

According to the Australian Government Department of Health, Cardarine GW-501516 is associated with a higher rate of numerous cancers.

Additionally, its toxicity could cause an increase in tumor formation.

Consistent with animal studies, Cardarine GW-501516 can cause cancer in mice.

The mutation of the cancer cells increases because of cell expansion.

For these reasons, cancer patients should avoid this drug until it has been proven to be effective for the treatment of cancer.

The Cons of Cardarine GW-501516

Apart from the contraindications, there are also some things to consider when it comes to Cardarine. In this section, we will discuss the disadvantages of using Cardarine.

1) Slow-acting 

Although Cardarine is an effective substance that can promote muscle gain, many users report that it is slow-acting. It takes around 2 months for the users to see the effects. 

Some selective androgen receptor modulators are fast-acting compared to this one. Usually, SARMs work as soon as 2 weeks.

If you are looking for SARM that can increase your lean muscle mass in no time, Cardarine might not be suitable for you.

2) Gastrointestinal discomfort

Another thing to be considered before taking Cardarine is that it can cause gastrointestinal discomforts like stomach cramps and constipation.

Although these may only occur during the first use of the drug, those with sensitive stomachs may experience these every time they take the drug.

Other side effects of Cardarine include nausea and vomiting, diarrhea, dizziness, lightheadedness, headache, flushing, insomnia, and swelling ankles/feet due to edema.

3) Overdose

Cardarine can promote weight loss.

However, when too much of it is taken, it could lead to overdose and some of the overdose symptoms include irregular heartbeat and high blood pressure.

Since this drug is still an investigational one, there is no established proper Cardarine dosage.

This means that anytime you take Cardarine, you are at risk of overdose.

If you wish to take Cardarine for medical purposes, you can ask a medical doctor about the proper dosage for you.

This dosage will depend on your current condition, your body goals, and other medications you take.

What People Say About Cardarine GW-501516

There are many Caradine users globally. Although this drug is not FDA-approved, they still take it as they believe it to help promote muscle growth.

In this section, we will have a look at what other people say about this drug.


Based on the user reviews above, Cardarine is an effective drug that can promote fat loss, and its fat-burning effects are optimal even at a low dose and short cycle. A dose of 10 mg per day can already burn fat.

Also, based on one user report, he saw an improvement in his cardiovascular performance.

Because of this, it is safe to say that Cardarine can truly support cardiovascular health, and this might be because Cardarine can also burn fat in the heart.

One user stated that he used Cardarine with Ostarine, and the use of these substances does not require post-cycle therapy. 

For potential users of Cardarine, it is worth mentioning that this drug increases muscle mass, promotes fat loss, and can support cardiovascular health.

What We Like About the Fat-Burner Cardarine

Cardarine can improve overall health and in this section, we will discuss how taking Cardarine can help you achieve this wellness.

1) Wound healing

One of the benefits of taking Cardarine is its anti-inflammatory effects. In animal studies, Cardarine was found to increase inflammatory responses.

As we all know, inflammation can impair muscle cells, which can eventually lead to a decline in athletic performance.

Thus, if Cardarine causes a reduced inflammation in your muscles, your ability to perform well increases.

2) Muscle mass enhancer

Taking Cardarine allows you to increase your muscle gains.

Based on clinical trials, Cardarine also promotes muscle hypertrophy.

In this study, it was reported that those who took Cardarine were able to increase 1.3 kgs of their muscle mass within 12 weeks.

Many users of this drug also reported improved endurance.

Eventually, this could lead to increased athletic performance.

3) Body fat loss

Cardarine is mainly used to reduce body fat. Its fat-burning effects can boost metabolism.

This means that this drug is an effective substance for managing body weight. Those with diabetes can improve insulin sensitivity.

Consistent with a study in Australia, the fat-burning effects of Cardarine can suppress glucose metabolism in the liver and combat insulin resistance.

Apart from helping you burn fat mass and reduce fat storage, Cardarine is used to prevent metabolic syndrome. 

4) Improved cholesterol levels

LDL cholesterol, also known as bad cholesterol, is dangerous to the heart.

When levels of this blood lipids increase, you become at a high risk of stroke. This happens because your blood vessels are also clogged with unhealthy fatty acids.

Fortunately, the use of Cardarine can improve your cholesterol levels.

This is associated with the fat-burning effects of the drug.

Generally, it triggers the AMP-activated protein kinase to increase fatty acid oxidation to reduce the fatty acids found in your heart.

5) No testosterone suppression

Most selective androgen receptor modulators can cause testosterone suppression, making them unsafe and not suitable for those with sexual dysfunction.

Fortunately, Cardarine does not give this side effect.

Cardarine does not affect your testosterone levels, but keep in mind that there are no studies about its activity in increasing testosterone levels as well.

6) No virilization in women

Virilization means developing male characteristics. Most SARMs can cause virilization and the most common one is gynecomastia.

Fortunately, Cardarine consumption does not cause virilization, making it safe for women who want to achieve weight loss, lose fat, or maintain muscle mass.

What to Watch Out for When Buying Cardarine

If you are an athlete, bodybuilder, or gym enthusiast, it is important to learn the following information for you to understand if this drug is suitable for you.

Although Cardarine is quite helpful for those who are interested in losing weight, this drug still comes with many side effects that can harm health.

Some of these side effects include gastrointestinal discomfort and insomnia.

This means that those with a sensitive stomach and those who are having sleep disturbances may not appreciate it.

Additionally, Cardarine consumption may cause an overdose. To know your Cardarine dosage, seek professional medical advice before use.

To know more about Cardarine, you can click here.

Caradine Drug Interactions

For those who are taking Cardarine with other medications, Cardarine may also interact with drugs.

Some of the drug interactions include thyroid medications, warfarin, and antibiotics.

Consult a pharmacist or a medical doctor if you are taking any of these drugs before taking Cardarine.

Buying Guide for Cardarine GW-501516

There are many ads over the net about Cardarine, and in this section, you will have a buying guide so that you can optimize both your money and health.

To introduce, Cardarine is available in oral and injection forms.

The oral route is safer than the IV as there are reports that IV treatment can cause cardiovascular risks.

Caradine and the World Anti-Doping Agency

Although Cardarine comes with fat-burning effects to help you lose weight, it is a banned substance by the World Anti-Doping Agency.

This means that Cardarine should not be used by athletes as this can cause disqualification. 

Additionally, the half-life of Cardarine is around 24 hours. Half-life means the time when half of the drug goes out of your system.

When you go for an anabolic steroid drug test, the metabolites of Caradine may cause a false-positive result on the drug test.

The Legal Cardarine Alternative: C-DINE 501516

C-DINE 501516

If you are looking for a Cardarine legal alternative to increase your lean mass, you might want to take a look at the C-DINE 501617.

This supplement is a Crazy Bulk brand and is used to improve the blood flow in the body.

Eventually, when there is proper blood flow, your blood vessels become free of stored fat.

According to the company, this Cardarine alternative can prevent liver disease and improve kidney health.

Additionally, it switches your glucose to fatty acids and uses these as your energy source. 

Other uses of this amazing supplement include maintenance of blood pressure, formation of new blood vessels in the heart, prevention of kidney disease, and increased energy production.

C-DINE 501516 Safe Use

Before buying C-DINE 501516, it is important to discuss its safe use.

According to the company, increasing fat burning effects are associated with a healthy diet and regular exercise.

You should also take this supplement for at least 3 months to see the optimal results.

Additionally, C-DINE 501516 is suitable for stacking. Most users take this supplement together with Ostarine.

C-DINE 501516 Formulation

C-DINE 501516 is one of the best supplements you can use if you want a higher energy source.

It enhances muscle endurance and can also support joint pain. Its ingredients include the following:

  • Vitamin C – This ingredient is used to support immunity and improve overall health. It also comes with antioxidant effects that can help you increase fatty acid oxidation.
  • Iron – This ingredient is used to reduce muscle fatigue. It also helps in speeding up the process of the formulation of new blood vessels and increases energy levels.
  • Vitamin B12 and B6 – These two are also used to reduce muscle fatigue and regenerate new brain cells. They help your body in producing energy as well.
  • Vitamin A – This ingredient supports your bone health and immunity. Some studies also report that vitamin A can reduce the risk of cancer and prevent liver disease.
  • Iodine – This ingredient enhances the body’s metabolism and reduces inflammation in the gut.
  • Chromium – This ingredient increases insulin sensitivity and improves lipid metabolism.
  • Southern ginseng – This ingredient is known to regulate blood pressure and reduce cholesterol. 

Apart from these, this amazing supplement also has two proprietary blends called InnoSlim and Capsimax.

These two are helpful for those who want to lose weight as they both can curb the appetite.

C-DINE 501516 Procurement Features

If you wish to take this Cardarine alternative, it is highly recommended to buy from the official website.

Getting C-DINE 501516 from the official web gives you many procurement benefits such as the following:

  • Free shipping on all orders
  • 100% 60-day money-back guarantee 
  • 2+1 deal and 3+2 deals

For additional discounts, you can subscribe using your email and get another 20% off on your first C-DINE 501516 order.

One great thing about the company is that it has 24/7 online chat support.

The agents here could help you find the best deals.

These agents are also helpful in case of shipping concerns and if you have other questions about the side effects of the supplement.


Indeed, the use of Cardarine can give many health benefits to the human body, especially for those who want to lose weight.

Some of the benefits of Cardarine include wound healing, muscle mass enhancement, and body weight management.

However, this drug is still an investigational one.

This means that its benefits and indications are not yet approved by the FDA.

Aside from these, Caradine is also contraindicated to some patients including pregnant and lactating women, those below 18 years old, and cancer patients.

Also, Cardarine may give a false-positive result on a drug test.

Thus, the use of alternatives like C-DINE 501516 is highly recommended.

If you wish to take this supplement, it is highly recommended to get it from the official website to get some great deals and many other procurement benefits.

Frequently Asked Questions (FAQs)

What are the most common side effects of Caradine?

The most common side effects of Cardarine include nausea and vomiting, diarrhea, dizziness, lightheadedness, headache, flushing, and insomnia. Some reports also state that Cardarine can cause cancer cell formation and edema.

Is Cardarine a SARM?

Technically, Cardarine is not a SARM. It is a metabolic modulator that can help you lose weight, improve your athletic performance, and prevent acute and chronic illnesses like diabetes, high blood pressure, and joint pain. Generally, it works by helping your body use fat as your source of energy.

How long does Cardarine work?

Some reports say that Cardarine can work as soon as 20 minutes. However, bodybuilders and gymnasts say that it may take up to 2 months for Cardarine to show its effects. Because of these, it is safe to say that the effects of Cardarine vary from one person to another, and there could be some factors associated with these effects, such as dosage and the current health condition of the user.

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