Gundry MD Bio Complete 3 Reviews: Side Effects, Ingredients, & Consumer Reports

bio complete 3 reviews

Welcome to my comprehensive Bio Complete 3 review…

You don’t have to be a health nut to know that good health starts with a healthy gut.

Numerous studies have demonstrated that the gut works behind the curtains to put our body in working order.

That is because the body obtains most of what it needs to function from the food you eat.

In your body, much of this food goes to either feeding disease or fighting it.

For instance, you’ll probably take aspirin or paracetamol to relieve the pain when you have a migraine headache.

In essence, you will have ingested something that helped fight off disease.

Likewise, eating too many fatty foods may cause a tummy ache.

And did you know that when you eat just ten calories (kcals) more than your body needs, you are likely to put on an extra 1 pound (lbs) in weight by the end year?

You probably don’t realize it, but you often eat garbage.

Many of the ‘foods’ we eat are already laden with bad stuff, to begin with.

Anything ‘extra’ you eat each day –those second helpings, a few greasy snacks, or even the scarps you cannot bear to toss out – eventually upsets the composition of your gut flora.

The gut flora consists of billions of microorganisms inside your digestive tract.

You’ve probably heard about bacteria in the gut helping in the digestion of food.

As it turns out, gut bacteria also play an essential role in your well-being and vulnerability to diseases.

If you want to stay healthy, taking foods promoting your gut health is paramount.

When it comes to gut health, nobody understands it better than Dr. Gundry.

We will talk more about him later and explain how his wellness brand, Gundry MD, has been at the forefront of improving human health through his unique vision of diet and nutrition.

One of Dr. Gundry’s wellness products, Bio Complete 3, is particularly important to this discussion.

That’s because Gundry MD Bio Complete 3 is a dietary supplement containing a blend of healthy ingredients important to your digestive and immune health.

Dr. Gundry Bio Complete 3 Review: Is It Worth it?

Gundry MD Bio Complete


We will show you how taking Bio Complete 3 will help you dramatically improve your overall health.

But first, we’ll begin with the fundamentals of gut health.

Why Gut health?

The incredible complexity of our gut and its influence on our overall well-being is a matter of increased research in medicine.

You will remember that the gut plays host to billions of microorganisms.

These organisms (microbes) are generally referred to as the gut microbiota.

They include bacteria, archaea, protists, fungi, and viruses.

However, bacteria are the most dominant microbes in the gut, and while some are good (beneficial) gut bacteria, others are bad.

When you have a healthy balance of gut bacteria, we call this state ‘equilibrium.’

So, when there is an imbalance in the gut microbiota, more harmful bacteria dominate the gut than the beneficial kind.

This loss of equilibrium inevitably throws the gut off and eventually compromises your immune system.

With a compromised immune system, you become vulnerable to autoimmune diseases, cases of flu and colds, allergies, skin and stomach issues, and various other conditions.

Unfortunately, most of our diet and lifestyle choices kill off the good gut bacteria and encourage the growth and development of harmful microbes.

This creates an imbalance that leaves the immune system compromised and unable to direct the gut microbiota back to a proper ratio, which is necessary to support a more favorable state of health and well-being for you, the host.

Studies have found that changes in the gut flora may cause diseases like Crohn’s disease, irritable bowel syndrome (IBS), and Ulcerative colitis.

It has also been responsible for pre-disposing people to more serious conditions like Diabetes, Autoimmune Thyroid Disease, Rheumatoid Arthritis, and other Autoimmune disorders.

Researchers are now working on new treatments for digestive issues by exploring the link between gut flora and the health conditions tied to its balance.

Solutions focusing on bacterial diversity in the gut flora have shown promise for treating some health issues that correlate with an unhealthy balance in the gut.

Studies suggest that food ingredients and dietary supplements like Dr. Gundry’s Bio Complete 3, which contain postbiotics, prebiotics, and probiotic strains, can help maintain a healthy digestive system and support a healthy immune system.

What is Bio Complete 3

Bio Complete 3 is a unique dietary supplement created by an accomplished heart surgeon and renowned author, Dr. Steven Gundry.

It is one of a range of wellness products and supplements branded ‘Gundry MD’ specially formulated to promote optimal health and wellbeing.

Gundry MD Bio Complete 3 is specially designed to support gut health.

It comes in vegetable capsules containing a unique blend of prebiotics, probiotics, and postbiotics.

According to Dr. Gundry MD, combining prebiotics, probiotics, and postbiotics into a single (one-size-fits-all) dietary supplement formula works to balance, restore, and nourish the gut microbiome and effectively…

  • Improve digestion and absorption of nutrients
  • Support a healthy gut lining, and
  • Promote optimal immune response.

Gundry MD claims that Bio Complete 3 can effectively produce a range of health benefits tied to optimal gut health and a strengthened Immune system by supporting gut health.

These health benefits may include:

  • Decreasing digestive issues,
  • Boosting energy levels and
  • Decreasing levels of fatigue,
  • Reducing cravings for unhealthy foods, and
  • Accelerating weight loss.

While scientific research on the health benefits of probiotic supplementation is still limited, the evidence gathered so far seems incredibly promising.

It is therefore not uncommon to hear of people claiming that probiotics like Dr. Steven Gundry’s Bio Complete 3 have helped ease symptoms of inflammatory bowel disease and conditions caused by dysfunction of the immune response, such as:

  • Irritable Bowel Syndrome (IBS)
  • Ulcerative colitis,
  • Celiac disease
  • Crohn’s Disease, and
  • Diabetes.

Several cases of people taking pre-and-probiotics regularly have yet to experience significant health benefits.

A few others have reported experiencing side effects within just a short period of use.

An important point to note here is that probiotics like Bio Complete 3 only ease the underlying symptoms of certain conditions (that affect or are affected by the digestive system).

Bio Complete 3 cannot treat or cure said medical conditions. Therefore, it should not be taken as a replacement for (traditional) prescription medicine.

Bio Complete 3 Ingredients

The label on your Bio Complete 3 bottle only lists three main natural ingredients, all of which are proprietary compounds registered and trademarked by third-party manufacturers certified by Gundry MD.

  • Tributyrin (as CoreBiome ®): 1000 mg
  • Sunfiber®: 200 mg
  • Bacillus Coagulans (ProDURA®) (2 billion CFU): 16 mg

The trio of primary ingredients in Bio Complete 3 is listed on the Supplement Facts label.

Bio Complete 3 contains a healthy blend of probiotics, prebiotics, and postbiotics, which are fundamental to your digestive health.

The label makes it possible to know what you are taking exactly, down to the amounts consumed per serving.

It features four other ingredients, as well, which are all safe and commonly used in other supplements and vitamin tablets:

  • Microcrystalline Cellulose
  • Hydroxypropyl Methylcellulose
  • Silica
  • Magnesium Stearate

It is impressive that Bio Complete 3, like other Gundry MD products, is candid about the additives and fillings used.

We will, however, only discuss further the supplement’s titular primary ingredients:

1) Tributyrin (1000 mg, as CoreBiome ®)

The Tributyrin portion allows for postbiotic supplementation.

Your Bio Complete 3 contains tributyrin sourced as CoreBiome ® from Compound Solutions, Inc.

CoreBiome ® Tributyrin supplies your body with the short-chain fatty acids (SCFA) required.

Butyrate is one of many short-chain fatty acids which your gut microbiota yields naturally when it ferments undigested dietary fibers in the colon.

Depletion of the short-chain fatty acid Butyrate is associated with intestinal injury and a weak immune response.

Tributyrate supplementation is beneficial for preserving a healthy gut lining due to the compound’s anti-inflammatory, hepatoprotective, and immunoprotective effects.

Various mechanisms have also been proposed to explain the effects of butyrate on alleviating obesity and producing promising effects in various diseases like diabetes and colorectal cancer.

The beneficial effect of tributyrin supplementation is still debatable since its actual mechanisms of action (MOA) on human health (more so the gut microbiome and the intestinal barrier) remains unclear.

Most research on the subject has only been conducted in animal laboratory studies.

Nevertheless, postbiotic supplementation has been shown to help create a healthy gut when combined with pre and probiotics.

2) Sunfiber®: 200 mg

Sunfiber makes up the prebiotic portion in your Gundry MD Bio Complete 3.

It is a pioneering brand of water-soluble dietary fiber derived from the Indian Guar Bean (Partially hydrolyzed guar gum, PHGG), developed and distributed by Taiyo International.

Based on research on the benefits of dietary fiber, we know that it plays a fundamental role in promoting a healthy balance in the GI tract.

It also functions as an alternative to promote and support healthy weight management by regulating the release of hunger hormones (ghrelin and leptin), which are associated with sensations of appetite and satiety.

A prominent study demonstrated that regular consumption of Sunfiber as a prebiotic supplement could produce the health benefits mentioned above.

Additionally, while it will not directly reduce your belly fat, Sunfiber has been proven to reduce cravings for unhealthy foods and thus help with weight loss.

A daily dose of Sunfiber 5g was also shown to support consistent bowel movements, normalize stool consistency, and promote good gut health.

Other clinically substantiated health benefits of Sunfiber listed on their website include:

  • Low fodmap and gluten-free
  • Prevent gas bloating
  • Prevent loose stools
  • Decrease post-meal glucose spikes.

Lastly, it is also quite impressive that this ingredient is qualified as a dietary fiber under the new Food and Drug Administration (FDA) stringent guidelines.

3) Bacillus Coagulans (16 mg, as ProDURA®)

Finally, the third primary ingredient of Gundry MD Bio Complete 3 is a probiotic bacteria called Bacillus Coagulans.

The ingredient containing these “beneficial” microorganisms is sourced as ProDURA®, a registered trademark of UAS Laboratories, located in Wausau, WI.

ProDURA® Bacillus Coagulans are a unique strain of spore-forming probiotic microorganisms sourced from spoilt milk.

The probiotic strains used in Bio Complete 3 are provided in a medial concentration of 2 billion CFU per gram.

Bacillus Coagulans were preferred due to their potential for treating gastrointestinal problems like gas bloating, diarrhea, and airway infections, which are also symptoms of the leaky gut syndrome and irritable bowel syndrome (IBS).

These digestive problems are usually set off by the overgrowth of harmful gut bacteria that kill off the good gut bacteria.

ProDURA® Bacillus Coagulans probiotics are designed to restore a balanced diversity of microorganisms by supporting the development and multiplication of beneficial bacteria over harmful bacteria in the gut.

Gundry MD prescribes 16 mg of ProDURA® (Bacillus Coagulans) probiotic bacteria to help support microbiota homeostasis and effectively promote better gut health by improving digestion.


Dr. Gundry MD recommends a dosage of four capsules daily, taken twice per day.

For optimal results, taking Bio Complete 3 regularly is advised.

The best time to take Bio Complete 3 supplements would be the morning before breakfast and an hour before dinner, preferably before dinner.

This routine has been found to offer twenty-four-hour protection for optimal gut health every day.

Note that the results may differ between users taking the same dose of Bio Complete 3.

Bio Complete 3 Side Effects & Safety

Most of the Bio Complete 3 ingredients listed on the label are considered relatively safe.

Some of these ingredients are approved by the Food and Drug Administration (FDA) and used in other nutrition supplements.

Gundry MD claims its wellness products have been tested for safety by an independent third-party facility.

Yet, there is no safety seal on the product label to back up said claims.

No matter, there are no significant safety concerns with Bio Complete 3, as with other probiotics and prebiotics.

And while side effects are common with probiotic supplements, they are mostly mild cases and do not cause serious concern.

The most common side effects that may occur include temporary cases of:

  • Dehydration
  • Gas bloating (Indigestion)
  • Diarrhea and
  • Constipation

Probiotic supplement capsules and powders generally have more severe side effects than gummies because they contain a higher concentration of probiotic strains.

Most experts recommend a probiotic rating of 10 billion CFU per gram.

However, Gundry MD Bio Complete 3 probiotic blend is rated at 2 billion CFU per gram.

Having the CFU rating on the lower end helps resolve some side effects without sacrificing the probiotics’ intended function of supporting smoother digestion for consistent bowel movements, maintaining a healthy microbiome, and helping deal with symptoms of leaky gut syndrome.

Dr. Steven Gundry: Founder, Gundry MD

Dr. Steven Gundry is one of the biggest names in the healthcare industry and perhaps one of the most accomplished medical experts in the world.

Dr. Gundry, MD, was the Head of Cardiothoracic Surgery at Loma Linda University Medical Center in California until stepping down from the position in 2002 to manage his clinic, The International Heart & Lung Institute for Restorative Medicine, in Palm Springs and Santa Barbara.

After leaving their distinguished career as a world-expert heart surgeon, Dr. Gundry spent the next twenty years studying the human microbiome.

During that time, he developed the principles of “Holobiotics” – a term he fabricated for his philosophy on the human microbiome.

He is now a renowned author, with his most popular, albeit perhaps also his most controversial, publication being the New York Times bestseller ‘The Plant Paradox.’

He also developed an entire wellness product line of supplements, skincare, haircare, and food products centered around his thoughts on the human microbiome.

Bio Complete 3 may not be Gundry MD’s most popular wellness product, but it is their best supplement for good gut health.

Its unique blend of prebiotics, probiotics, and postbiotics helps restore equilibrium to the gut microbiota quickly.

And with a design centered around the concept of “Holobiotics,” Bio Complete 3 works more than a solution for improving digestive health but also an effective boost for the host’s immune responses.

Bio Complete Testimonials from Customers

You shouldn’t be surprised to find that most of Bio Complete 3 reviews and testimonials are positive. Here’s what customers are saying.

I was highly skeptical about dietary supplements at first. But after combing through myriad customer reviews, I was convinced enough to try Dr. Gundry’s Bio Complete 3. It didn’t do much in the way of helping with my weight management initially, aside from experiencing some discomfort. However, after a couple of days, I realized that I no longer had unhealthy cravings. Normally, I’d go through a whole pack of cookies and a large bag of chips with no problem. I am eager to see how this reflects on the scales.

Nothing was going to work for my long-lasting digestive issues.So the Gundry MD website was just one in a long line of internet sites I have gone through in my quest to find a ‘good gut.’ Dr. Steven Gundry put up quite promising claims, and while I didn’t really fully understand his talk on “Holobiotics,” one thing was evident to me; he was an expert in his field, and the guy actually developed the dietary supplement formulas to help with his own health issues. Well into my last bottle of the 3-pack I ordered, and I’m impressed with the results. I can honestly say that I feel much better now. I’ve seen a significant boost in energy levels, and I’m having softer, more consistent bowel movements. It’s important, I think, to take Bio Complete 3 capsules twice per day, preferably before your largest meal.

Cost & Shipping

The total cost of your Bio Complete 3 formula will depend on the number of bottles you wish to order. Gundry MD provides 3 order options with 30 capsules contained in each bottle:

  • 1 Bottle
  • 3 Bottles
  • 6 Bottles

For your first order, we recommend going for the one-bottle option.

This will help you evaluate Gundry Md’s probiotic formula without purchasing more of the product than is necessary.

Of course, you get a discount (per bottle) when you order the 3-bottle or 6-bottle options.

What’s more, you get free shipping with multiple-bottle order options.

So there’s that consideration as well.

A single bottle of Bio Complete 3 supplement may seem costly compared to similar dietary supplements.

However, you mustn’t forget that Gundry Md’s probiotics formula is higher quality than regular probiotic products because of its unique 3-pronged blend of probiotics, prebiotics, and postbiotics.

Unlike other Gundry MD products, all Bio Complete 3 purchases are covered by a 100% Satisfaction 90-day money-back guarantee.

With the straightforward 90-day money-back guarantee and full refund policy on all wellness products in their catalog, Gundry MD empowers its buyers to shop confidently.

You will find that this refund guarantee is quite a generous return policy as most other similar brands offer shorter guarantee periods of 30 and 60 days or a 90-day money-back guarantee on eligible purchases.

Quick Overview


  • Doctor formulated supplement
  • Good for gut health
  • Helps with weight loss
  • Improves bowel movements
  • Safe ingredients in effective dosage
  • Unconditional money-back guarantee
  • Excellent customer service
  • Free shipping


  • Lacks complete disclosure of ingredients
  • High-quality probiotics are expensive

Where to Buy

You can only buy Gundry MD wellness products from their official website.

Any Gundry MD products you find in other online stores are from resellers and may not be genuine products.

You can get exclusive deals with Bio Complete 3 when you sign up for the Gundry MD website.

Gundry MD also offers additional discounts off all Bio Complete 3 packages when you sign up for a subscription.

You will receive exclusive offers direct to your email.

However, I’d advise not signing up for anything until you’ve tried your first Bio Complete 3 probiotics bottle.

Subscribe only if the first bottle showed promising results and you wish to have recurring orders to help maintain a healthier lifestyle.

Bottom Line: Does it Work?

It’s impressive that Dr. Steven Gundry, MD, is transparent about how his wellness products are created, packaged, labeled, and sold.

It is also commendable that his brand, Gundry MD, ensures that all products are tested for safety by an independent third-party facility.

At this point, I feel pressured to say that Dr. Gundry’s Bio Complete 3 will…

  • Help take care of your digestive system
  • Help with weight loss
  • Ease the symptoms of inflammatory bowel disease and
  • Improve your health altogether, but this claim would be purely based on the plethora of favorable customer reviews on the company website.

There is no way to know for sure what to expect after taking bio complete 3.

But with a 90-day money-back guarantee, Dr. Steven Gundy, MD, assures you of positive results, or you’ll get your money back, no questions asked.